Güncel Gönderiler: Araştırma Çıktıları (TR Dizin / Web of Science / Scopus / PubMed)
Toplam kayıt 1547, listelenen: 1321-1340
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Clostridium botulinumneurotoxin A induces apoptosis and mitochondrial oxidative stress via activation of TRPM2 channel signaling pathway in neuroblastoma and glioblastoma tumor cells
(Taylor & Francis Ltd, 2020)Background TheClostridium botulinumneurotoxin A (BTX) is a polypeptide produced by the bacteriumClostridium botulinum. In addition to the therapeutic actions of BTX against pain and neuromuscular disorders, it is acted as ... -
Recurrent binary patterns and CNNs for offline signature verification
(Springer International Publishing Ag, 2020)Signature representations that are extracted by convolutional neural networks (CNN) can achieve low error rates. However, a trade-off exists between such models' complexities and hand-crafted features' slightly higher error ... -
Applicability of thermophotovoltaic technologies in the iron and steel sectors
(Wiley-V C H Verlag Gmbh, 2018)The theoretical potential for converting excess heat from the iron and steel sectors in Turkey into electricity by the use of thermophotovoltaic (TPV) systems is investigated and analyzed. The TPV usage in this industry ... -
Chocolate aroma: Factors, importance and analysis
(Elsevier Science London, 2020)Background: The quality and value of chocolate are related to its unique and fascinating flavor arisen from volatile and non-volatile compounds present in the product. The particular chocolate aroma is dependent on various ... -
Bayesian estimation of student-t garch model using lindley's approximation
(Acad Economic Studies, 2019)The dependency of conditional second moments of financial time series is modelled by Generalized Autoregressive conditionally heteroscedastic (GARCH) processes. The maximum likelihood estimation (MLE) procedure is most ... -
Ameliorative effects of pregabalin on LPS induced endothelial and cardiac toxicity
(Taylor & Francis Ltd, 2020)We investigated the antioxidant, anti-inflammatory and anti-apoptotic effects of pregabalin (PREG) on lipopolysaccharide (LPS) induced sepsis related cardiotoxicity via NF-k beta pathways. We used 24 female Wistar albino ... -
The relationship between ureteral obstruction time and secondary signs in computed tomography due to ureteral stone obstruction
(Coll Physicians & Surgeons Pakistan, 2020)Objective: To investigate the relationship between numerical values obtained using computed tomography (CT) in stone-related urinary obstruction and the duration of obstruction. Study Design: Cross-sectional study. Place ... -
Bilateral post-traumatic facial paralysis that contains longitudinal and transverse temporal fracture
(Lippincott Williams & Wilkins, 2018)Acute bilateral post-traumatic facial paralysis is rare in the literature. Post-traumatic facial paralysis is frequently accompanied transverse fractures of temporal more. The incidence of acute bilateral post-traumatic ... -
Retroperitoneal teratoma with secondary infection
(Coll Physicians & Surgeons Pakistan, 2019)Teratomas are germ cell tumors arising from the embryonic germ layers. Since they originate from the germ cells, they can be found in the gonadal, sacrococcygeal, mediastinal, intracranial, retroperitoneal, and cervical ... -
Cetuximab and epirubicin HCl-combined application as a possibility to treat both parental and epirubicin HCl-resistant liver cancer cells
(Akademiai Kiado Zrt, 2019)Background and aims: Targeted chemotherapeutics such as cetuximab can cause many side effects such as skin toxicity when used in high concentrations. In addition, cancer cells can develop resistance to some of the anticancer ... -
Evaluation of the relationship between body composition and aerobic fitness in youth soccer players
(Natl Olympic Committee Ukraine, Kharkov Regional Branch, 2018)Purpose: The purpose of the study was to make an evaluation between aerobic fitnes (VO2max) and body composition in youth soccer players. Material: U19, U17, U16 and U15 age groups participated in the study. Twenty-eight ... -
Minocycline increases in-vitro cortical neuronal cell survival after laser induced axotomy
(Bentham Science Publ Ltd, 2020)Background: Antibiotic therapies targeting multiple regenerative mechanisms have the potential for neuroprotective effects, but the diversity of experimental strategies and analyses of non-standardised therapeutic trials ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells
(Springer, 2020)Purpose Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood. Temozolomide is used for treatment in high-risk groups with low treatment response of neuroblastomas. ... -
The effect of intracerebral structure volumes on idiopathic intracranial hypertension
(Lippincott Williams & Wilkins, 2021)Background This aim of this study was to assess the effect of idiopathic intracranial hypertension (IIH) in the development of intracranial hypertension by measuring patients' cerebrospinal fluid (CSF), brain, and segment ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells (vol 21, pg 541, 2020)
(Springer, 2020)[No abstract available] -
Protective effects of N-acetyl cysteine against paclitaxel-induced cardiotoxicity through modulation of transient receptor potential melastatin 2 channels
(Gazi Univ, Fac Med, 2019)Aim : In our study, we investigated the paclitaxel induced cardiotoxicity and alterations in Ca2+ influx, oxidative stress and apoptosis through transient receptor potential melastatin 2 (TRPM2) channels and modulator role ... -
Using action research based on the predict-observe-explain strategy for teaching enzymes
(Mehmet Tekerek, 2016)The science laboratory course is one of the important courses that preservice science students take in their science education programs. The purpose of this study is to investigate the impact of an action research based ... -
Synergic and comparative effect of 5-fluorouracil and leucoverin on breast and colon cancer cells through TRPM2 channels
(Comenius Univ, 2018)OBJECTIVES: We aimed to reveal the role of 5-fluorouracil (5-FU) and Leucovorin (LV) along with transient receptor potential protein melastatin 2 (TRPM2) channels in breast and colon cancer cells during the treatment ... -
The effect of melatonin on digoxin-induced cardiac damage in cardiomyocytes
(Comenius Univ, 2019)OBJECTIVES: Digoxin is a cardiac glycoside which is widely used in cardiovascular medicine. Oxidative stress, as well as intracellular Ca2+ overload, plays an important role in digoxin toxicity. Transient receptor potential ... -
The role of selenium in bevacizumab induced cardiotoxicity
(Comenius Univ, 2019)OBJECTIVE: We investigated the role of selenium in bevacizumab induced cardiotoxicity and involvement of transient receptor potential vanilloid 1 (TRPV1) channels in cardiomyocytes. MATERIALS AND METHODS: All cells (Human ...