Yazar "Övey, İshak Suat" için listeleme
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Alzheimer Hastalığının Önlenmesi ve Tedavisinde Melatoninin TRPA1 Kanalları Üzerinden Potansiyel Etkileri
Özşimşek, Ahmet; Övey, İshak Suat (2022)Amaç: Alzheimer hastalığı (AH) demansın en yaygın nedenidir ve ilerleyici bir nörodejeneratif hastalık olarak tanımlanır. AH ilerleyici bozukluğunun ana klinik özellikleri öğrenme ve hafıza kaybıdır. Çeşitli çalışmalar ... -
Antalya'da sağlık turizmi yetki belgesi olan kurumlarda dijital pazarlamanın etkisi
Fırtına İlhan, Candan (Alanya Alaaddin Keykubat Üniversitesi / Lisansüstü Eğitim Enstitüsü, 2023)Turizm alanında katma değeri en yüksek turizm türlerinden biri olan Sağlık Turizmine olan ilgi her geçen gün artmaktadır. İnternet teknolojilerinin yayılımıyla sağlık alanında uygulanan yeni tedavi yöntemleri hakkında ... -
Apoptotic efficiency of capecitabine and 5-fluorouracil on human cancer cells through TRPV1 channels
Övey, İshak Suat; Güler, Yılmaz (Natl Inst Science Communication-Niscair, 2020)The expression of transient receptor potential protein channels increases intensively colon and breast cancer cells. We aimed to reveal the role of 5-fluorouracil (5FU) and capecitabine along with Transient Receptor Potential ... -
Effect of astaxanthin in imatinib mesylate-induced cardiotoxicity
Övey, İshak Suat; Öncel, Can Ramazan (Alanya Alaaddin Keykubat Üniversitesi, 2020)Aim: Imatinib mesylate is a tyrosine kinase inhibitor and is approved as a standard first-line therapy of chronic myeloid leukemia. Oxidative stress, as well as intracellular calcium overload and mitochondrial dysfunction, ... -
The effect of melatonin on digoxin-induced cardiac damage in cardiomyocytes
Övey, İshak Suat; Öncel, Can Ramazan (Comenius Univ, 2019)OBJECTIVES: Digoxin is a cardiac glycoside which is widely used in cardiovascular medicine. Oxidative stress, as well as intracellular Ca2+ overload, plays an important role in digoxin toxicity. Transient receptor potential ... -
The effects of carvacrol on oxidative stress parameters and adoptosis process via TRPA1 channels in neuroblastoma cells
Günal, Mehmet Yalçın; Övey, İshak Suat (Polskie Towarzystwo Farmaceutyczne, 2019)Objectives: This study is a preliminary study to investigate the effects of carvacrol (CRV) obtained from thyme on the apoptosis process in neuroblastoma cells. Methods: In this study, seven groups were designed as control, ... -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels in in-vitro model of alzheimer's disease
Övey, İshak Suat; Nazıroğlu, Mustafa (Wiley, 2018)[No abstract available] -
Effects of homocysteine and memantine on oxidative stress related TRP cation channels inin-vitromodel of Alzheimer's disease
Övey, İshak Suat; Nazıroğlu, Mustafa (Taylor & Francis Ltd, 2020)Memantine (MEM) has been used to treat patients with Alzheimer' disease though inhibition of reactive oxygen species (ROS), Ca(2+)entry and glutamate receptor. The Ca(2+)permeable TRPA1, TRPM2 and TRPV1 channels are activated ... -
LLLT enhance cyclophosphamide induced TRPM2 channel activation in human colon cancer cells
Güler, Yılmaz; Övey, İshak Suat (Comenius Univ, 2020)AIM: Transient receptor potential (TRP) channels expression is enhanced significantly in colon cancer cells and Low Lever Laser Treatment (LLLT), is known to have effects and is used clinically in the treatment ofmany ... -
Low level laser application reduces the effect of 5 fluorouracil/leucovorin combination on human breast cancer cells
Aim : 5-fluorouracil has been widely used in breast cancer treatment. Low level laser therapy (LLLT) has been shown to modulate biological processes and used in cancer treatment. It has been reported that apoptosis is ... -
Protective effects of N-acetyl cysteine against paclitaxel-induced cardiotoxicity through modulation of transient receptor potential melastatin 2 channels
Öncel, Can Ramazan; Övey, İshak Suat (Gazi Univ, Fac Med, 2019)Aim : In our study, we investigated the paclitaxel induced cardiotoxicity and alterations in Ca2+ influx, oxidative stress and apoptosis through transient receptor potential melastatin 2 (TRPM2) channels and modulator role ... -
The role of selenium in bevacizumab induced cardiotoxicity
Öncel, Can Ramazan; Övey, İshak Suat (Comenius Univ, 2019)OBJECTIVE: We investigated the role of selenium in bevacizumab induced cardiotoxicity and involvement of transient receptor potential vanilloid 1 (TRPV1) channels in cardiomyocytes. MATERIALS AND METHODS: All cells (Human ... -
Sağlık Turizmi Kapsamında Biorezonans Uygulamaları
Doğmuş, Bahadır Bektaş (Alanya Alaaddin Keykubat Üniversitesi / Lisansüstü Eğitim Enstitüsü, 2024)Geçtiğimiz yüzyılın en önemli bilim insanlarından, mucitlerinden ve dâhilerinden biri olan Nikola Tesla'nın "Eğer evrenin sırlarını bulmayı arzuluyorsanız enerji, frekans ve titreşimler üzerinden düşünün." sözü ışığında ... -
Sağlık turizmi kapsamında; nadir hastalıkların tedavisinde Türkiye'nin potansiyeli
Balıktay, Yasemin (Alanya Alaaddin Keykubat Üniversitesi / Lisansüstü Eğitim Enstitüsü / Sağlık Turizmi Ana Bilim Dalı, 2021)Nadir hastalıklardan tanı alan hasta sayılarının hem ülkemizde hem de dünya genelinde gün geçtikçe artması, bu hastalıklarla mücadele eden hastaların ve yakınlarının tanı ve tedavi süreçlerinde zorlanmaları nedeniyle ... -
Selenium enhances the TRPM2 mediated effect of paclitaxel on human breast cancer cells
Güler, Yılmaz; Övey, İshak Suat (2020)Abstract Aim: Paclitaxel is widely used in adjuvant treatment of early breast cancer and second-line treatment of metastatic breast cancer. It has been reported that transient receptor potential melastatin-2 (TRPM2) channels ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells
Özkal, Birol; Övey, İshak Suat (2020)Purpose Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood. Temozolomide is used for treatment in high-risk groups with low treatment response of neuroblastomas. ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells
Özkal, Birol; Övey, İshak Suat (Springer, 2020)Purpose Neuroblastoma is a malignant solid tumor that originates from the sympathetic nervous system in early childhood. Temozolomide is used for treatment in high-risk groups with low treatment response of neuroblastomas. ... -
Selenium enhances TRPA1 channel-mediated activity of temozolomide in SH-SY5Y neuroblastoma cells (vol 21, pg 541, 2020)
Özkal, Birol; Övey, İshak Suat (Springer, 2020)[No abstract available] -
Sisplatin uygulanan pankreas ve mide kanseri hücrelerinde melatoninin TRPV1 kanalları aracılı rolü
Yur, Ayşegül (Alanya Alaaddin Keykubat Üniversitesi,Lisansüstü Eğitim Enstitüsü, 2022)Mide ve pankreas kanserleri toplumda sıkça görülen ve mortalite oranları yüksek kanser çeşitleridir. Sisplatin, DNA hasarına neden olan ve birçok kanser türünün tedavisinde tercih edilen neoplastik bir ajandır. Mevcut tez ...
